|Other Names||Eukaryotic translation initiation factor 2-alpha kinase 4, GCN2-like protein, mGCN2, Eif2ak4, Gcn2, Kiaa1338|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Can phosphorylate the alpha subunit of EIF2 and may mediate translational control.|
|Tissue Location||Expressed in liver (at protein level). Widely expressed, with the highest levels in the liver and the brain Isoform 4 is expressed in brain followed by testis and liver and isoform 3 is expressed only in brain|
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Provided below are standard protocols that you may find useful for product applications.
Eif2ak4 can phosphorylate the alpha subunit of EIF2 and may mediate translational control.
Bunpo, P., et al. J. Nutr. 140(11):2020-2027(2010)Ye, J., et al. EMBO J. 29(12):2082-2096(2010)Liu, Y., et al. Neoplasia 12(1):61-68(2010)Jasperson, L.K., et al. Blood 114(24):5062-5070(2009)Bunpo, P., et al. J. Biol. Chem. 284(47):32742-32749(2009)
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