NLGN4X Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8N0W4 |
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Clone Names | 100517014 |
Gene ID | 57502 |
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Other Names | Neuroligin-4, X-linked, Neuroligin X, HNLX, NLGN4X, KIAA1260, NLGN4 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | NLGN4X |
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Synonyms | KIAA1260, NLGN4 |
Function | Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. |
Cellular Location | Cell membrane; Single-pass type I membrane protein. Postsynaptic density membrane |
Tissue Location | Expressed at highest levels in heart. Expressed at lower levels in liver, skeletal muscle and pancreas and at very low levels in brain. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of a family of neuronal cellsurface proteins. Members of this family may act as splicesite-specific ligands for beta-neurexins and may be involved in theformation and remodeling of central nervous system synapses. Theencoded protein interacts with discs, large (Drosophila) homolog 4(DLG4). Mutations in this gene have been associated with autism andAsperger syndrome. Two transcript variants encoding the sameprotein have been identified for this gene.
References
Kelemenova, S., et al. Psychiatr. Genet. 20(4):137-139(2010)Leone, P., et al. EMBO J. 29(14):2461-2471(2010)Zhang, K., et al. Neuropsychobiology 62(4):221-228(2010)Zhang, C., et al. J. Neurosci. 29(35):10843-10854(2009)Guilmatre, A., et al. Arch. Gen. Psychiatry 66(9):947-956(2009)
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