|Other Names||Growth arrest and DNA damage-inducible protein GADD45 gamma, Cytokine-responsive protein CR6, DNA damage-inducible transcript 2 protein, DDIT-2, GADD45G, CR6, DDIT2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.|
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This gene is a member of a group of genes whose transcriptlevels are increased following stressful growth arrest conditionsand treatment with DNA-damaging agents. The protein encoded by thisgene responds to environmental stresses by mediating activation ofthe p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highlyexpressed in placenta.
Flores, O., et al. Endocrinology 151(10):4654-4664(2010)Zhang, W., et al. J. Cancer Res. Clin. Oncol. 136(8):1267-1273(2010)Zhu, N., et al. Mol. Biol. Rep. 36(8):2075-2085(2009)Yu, S., et al. Am. J. Nephrol. 30(2):135-139(2009)Palmieri, R.T., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3567-3572(2008)
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