|Other Names||Regulator of G-protein signaling 16, RGS16, A28-RGS14P, Retinal-specific RGS, RGS-r, hRGS-r, Retinally abundant regulator of G-protein signaling, RGS16, RGSR|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha. May play a role in regulating the kinetics of signaling in the phototransduction cascade.|
|Tissue Location||Abundantly expressed in retina with lower levels of expression in most other tissues|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene belongs to the 'regulatorof G protein signaling' family. It inhibits signal transduction byincreasing the GTPase activity of G protein alpha subunits. It alsomay play a role in regulating the kinetics of signaling in thephototransduction cascade.
Wang, J., et al. Carcinogenesis 31(10):1755-1761(2010)Kim, J.H., et al. Tumour Biol. 31(5):541-548(2010)Miyoshi, N., et al. Ann. Surg. Oncol. 16(12):3507-3514(2009)Liang, G., et al. J. Biol. Chem. 284(32):21719-21727(2009)Wiechec, E., et al. Genes Chromosomes Cancer 47(9):766-780(2008)
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