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RGS16 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession O15492
Clone Names 100525293
Peptide ID 100525293
Additional Information
Gene ID 6004
Other Names Regulator of G-protein signaling 16, RGS16, A28-RGS14P, Retinal-specific RGS, RGS-r, hRGS-r, Retinally abundant regulator of G-protein signaling, RGS16, RGSR
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RGS16
Synonyms RGSR
Function Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:11602604, PubMed:18434541). Plays an important role in the phototransduction cascade by regulating the lifetime and effective concentration of activated transducin alpha. May regulate extra and intracellular mitogenic signals (By similarity).
Cellular Location Membrane {ECO:0000250|UniProtKB:P97428}; Lipid-anchor {ECO:0000250|UniProtKB:P97428}
Tissue Location Abundantly expressed in retina with lower levels of expression in most other tissues
Research Areas
Citations (0)

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Background

The protein encoded by this gene belongs to the 'regulatorof G protein signaling' family. It inhibits signal transduction byincreasing the GTPase activity of G protein alpha subunits. It alsomay play a role in regulating the kinetics of signaling in thephototransduction cascade.

References

Wang, J., et al. Carcinogenesis 31(10):1755-1761(2010)Kim, J.H., et al. Tumour Biol. 31(5):541-548(2010)Miyoshi, N., et al. Ann. Surg. Oncol. 16(12):3507-3514(2009)Liang, G., et al. J. Biol. Chem. 284(32):21719-21727(2009)Wiechec, E., et al. Genes Chromosomes Cancer 47(9):766-780(2008)

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$ 80.00
Cat# BP14770a
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