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RGS16 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O15492 |
|---|---|
| Clone Names | 100525293 |
| Gene ID | 6004 |
|---|---|
| Other Names | Regulator of G-protein signaling 16, RGS16, A28-RGS14P, Retinal-specific RGS, RGS-r, hRGS-r, Retinally abundant regulator of G-protein signaling, RGS16, RGSR |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | RGS16 |
|---|---|
| Synonyms | RGSR |
| Function | Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP- bound form (PubMed:11602604, PubMed:18434541). Plays an important role in the phototransduction cascade by regulating the lifetime and effective concentration of activated transducin alpha. May regulate extra and intracellular mitogenic signals (By similarity). |
| Cellular Location | Membrane {ECO:0000250|UniProtKB:P97428}; Lipid- anchor {ECO:0000250|UniProtKB:P97428} |
| Tissue Location | Abundantly expressed in retina with lower levels of expression in most other tissues |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene belongs to the 'regulatorof G protein signaling' family. It inhibits signal transduction byincreasing the GTPase activity of G protein alpha subunits. It alsomay play a role in regulating the kinetics of signaling in thephototransduction cascade.
References
Wang, J., et al. Carcinogenesis 31(10):1755-1761(2010)Kim, J.H., et al. Tumour Biol. 31(5):541-548(2010)Miyoshi, N., et al. Ann. Surg. Oncol. 16(12):3507-3514(2009)Liang, G., et al. J. Biol. Chem. 284(32):21719-21727(2009)Wiechec, E., et al. Genes Chromosomes Cancer 47(9):766-780(2008)
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