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ALDH8A1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9H2A2
Additional Information
Gene ID 64577
Other Names Aldehyde dehydrogenase family 8 member A1, 121-, Aldehyde dehydrogenase 12, ALDH8A1, ALDH12
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1479b was selected from the C-term region of human ALDH8A1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ALDH8A1
Synonyms ALDH12
Function Converts 9-cis-retinal to 9-cis-retinoic acid. Has lower activity towards 13-cis-retinal. Has much lower activity towards all-trans-retinal. Has highest activity with benzaldehyde and decanal (in vitro). Has a preference for NAD, but shows considerable activity with NADP (in vitro).
Cellular Location Cytoplasm.
Tissue Location Highly expressed in adult kidney and liver. Detected at lower levels in fetal liver and kidney
Research Areas
Citations (0)

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ALDH8A1 belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal.


Lin,M.,J. Biol. Chem. 275 (51), 40106-40112 (2000)

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$ 80.00
Cat# BP1479b
(40 western blots)
Availability: In Stock
Bulk Size
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