|Other Names||Homeobox protein OTX1, Orthodenticle homolog 1, OTX1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.|
|Tissue Location||Expressed in brain. Detected in the anterior part of the neural fetal retina (at protein level)|
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This gene encodes a member of the bicoid sub-family ofhomeodomain-containing transcription factors. The encoded proteinacts as a transcription factor and may play a role in brain andsensory organ development. A similar protein in mice is requiredfor proper brain and sensory organ development and can causeepilepsy.
Larsen, K.B., et al. J. Histochem. Cytochem. 58(7):669-678(2010)Omodei, D., et al. Am. J. Pathol. 175(6):2609-2617(2009)Eeles, R.A., et al. Nat. Genet. 41(10):1116-1121(2009)Larsen, K.B., et al. Int. J. Dev. Neurosci. 27(5):485-492(2009)Xin, X., et al. Genome Res. 19(7):1262-1269(2009)
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