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TRIM2 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9C040 |
|---|---|
| Clone Names | 100408310 |
| Gene ID | 23321 |
|---|---|
| Other Names | Tripartite motif-containing protein 2, 632-, E3 ubiquitin-protein ligase TRIM2, RING finger protein 86, TRIM2, KIAA0517, RNF86 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | TRIM2 |
|---|---|
| Synonyms | KIAA0517, RNF86 |
| Function | UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance. Plays a role in antiviral immunity and limits New World arenavirus infection independently of its ubiquitin ligase activity (PubMed:24068738). |
| Cellular Location | Cytoplasm. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a member of thetripartite motif (TRIM) family. The TRIM motif includes threezinc-binding domains, a RING, a B-box type 1 and a B-box type 2,and a coiled-coil region. The protein localizes to cytoplasmicfilaments. Its function has not been identified. [provided byRefSeq].
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :Ohkawa, N., et al. J. Neurochem. 78(1):75-87(2001)Reymond, A., et al. EMBO J. 20(9):2140-2151(2001)
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