|Other Names||Cardiotrophin-1, CT-1, CTF1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor.|
|Tissue Location||Highly expressed in heart, skeletal muscle, prostate and ovary. Lower levels in lung, kidney, pancreas, thymus, testis and small intestine. Little or no expression in brain, placenta, liver, spleen, colon or peripheral blood leukocytes|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a secreted cytokinethat induces cardiac myocyte hypertrophy in vitro. It has beenshown to bind and activate the ILST/gp130 receoptor. Two transcriptvariants encoding different isoforms have been found for this gene.
Robador, P.A., et al. J. Hypertens. (2010) In press :Bailey, S.D., et al. Diabetes Care (2010) In press :Limongelli, G., et al. Cytokine 50(3):245-247(2010)Zimmerman, R.S., et al. Genet. Med. 12(5):268-278(2010)Fritzenwanger, M., et al. Mediators Inflamm. 2009, 489802 (2009) :
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