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TADA2L Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O75478
Clone Names 100528096
Peptide ID 100528096
Additional Information
Gene ID 6871
Other Names Transcriptional adapter 2-alpha, Transcriptional adapter 2-like, ADA2-like protein, TADA2A, TADA2L
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms TADA2L
Function Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double- stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling.
Cellular Location Nucleus. Chromosome.
Tissue Location Expressed in all tissues, but most abundantly in testis
Research Areas
Citations (0)

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Many DNA-binding transcriptional activator proteinsenhance the initiation rate of RNA polymerase II-mediated genetranscription by interacting functionally with the generaltranscription machinery bound at the basal promoter. Adaptorproteins are usually required for this activation, possibly toacetylate and destabilize nucleosomes, thereby relieving chromatinconstraints at the promoter. The protein encoded by this gene is atranscriptional activator adaptor and has been found to be part ofthe PCAF histone acetylase complex. Several alternatively splicedtranscript variants encoding different isoforms of this gene havebeen described, but the full-length nature of some of thesevariants has not been determined.


Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)Yang, M., et al. Cancer Biol. Ther. 7(1):120-128(2008)Lamesch, P., et al. Genomics 89(3):307-315(2007)Qian, C., et al. Nat. Struct. Mol. Biol. 12(12):1078-1085(2005)Barlev, N.A., et al. Mol. Cell. Biol. 23(19):6944-6957(2003)

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$ 80.00
Cat# BP14912c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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