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Mouse Clk3 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O35492
Clone Names 110316109
Peptide ID 110316109
Additional Information
Gene ID 102414
Other Names Dual specificity protein kinase CLK3, CDC-like kinase 3, Clk3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Clk3
Function Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Phosphorylates SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.
Cellular Location Nucleus. Cytoplasm. Cytoplasmic vesicle, secretory vesicle, acrosome
Tissue Location Present at high levels in testis and ovary. In testis, expression is restricted to elongated, maturing spermatozoa. Also present in spleen, brain, lung and liver (at protein level).
Research Areas
Citations (0)

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Phosphorylates serine-and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates serines, threonines and tyrosines.


Sansom, S.N., et al. PLoS Genet. 5 (6), E1000511 (2009) :Carrier, A., et al. Immunogenetics 50 (5-6), 255-270 (1999) :Nayler, O., et al. Biochem. J. 326 (PT 3), 693-700 (1997) :

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$ 80.00
Cat# BP14953a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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