|Other Names||Homeobox protein BarH-like 1, BARX1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor, which is involved in craniofacial development, in odontogenesis and in stomach organogenesis. May have a role in the differentiation of molars from incisors. Plays a role in suppressing endodermal Wnt activity (By similarity). Binds to a regulatory module of the NCAM promoter.|
|Tissue Location||Widely expressed. Expressed at higher levels in testis and heart. Detected in craniofacial tissue and adult iris, but not in lymphocytes, fibroblasts, choroid retina, retinal pigment epithelium, kidney, or fetal liver|
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This gene encodes a member of the Bar subclass of homeoboxtranscription factors. Studies of the mouse and chick homologsuggest the encoded protein may play a role in developing teeth andcraniofacial mesenchyme of neural crest origin. The protein mayalso be associated with differentiation of stomach epithelia.
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008)Krivicka-Uzkurele, B., et al. Stomatologija 10(2):62-66(2008)Lowry, R.B., et al. Am. J. Med. Genet. A 143A (11), 1227-1230 (2007) :Gould, D.B., et al. Genomics 68(3):336-342(2000)
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