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Connexin 32 Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P08034
Clone Names 2051707
Additional Information
Gene ID 2705
Other Names Gap junction beta-1 protein, Connexin-32, Cx32, GAP junction 28 kDa liver protein, GJB1, CX32
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1541a was selected from the N-term region of human GJB1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GJB1
Synonyms CX32
Function One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Cellular Location Cell membrane; Multi-pass membrane protein. Cell junction, gap junction
Research Areas
Citations (0)

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Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels.GJB1 is normally found in the paranodal myelin loops and Schmidt-Lanterman incisures of myelinating Schwann cells in the peripheral nervous system, as well as in oligodendrocytes and their processes, but not in compact myelin of the central nervous system. A series of mutational and other studies have directly linked defects in GJB1 to X-linked Charcot-Marie-Tooth disease (CMTX), a clinically and genetically heterogeneous group of hereditary motor and sensory peripheral neuropathies.


Yang, J., et al., Biochem. Biophys. Res. Commun. 307(1):80-85 (2003).Sahin, N., et al., Int. J. Neurosci. 113(6):777-785 (2003).Ma, X.D., et al., World J. Gastroenterol. 9(5):946-950 (2003).Takashima, H., et al., Acta Neurol Scand 107(1):31-37 (2003).Govindarajan, R., et al., J. Biol. Chem. 277(51):50087-50097 (2002).

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$ 80.00
Cat# BP1541a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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