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GJB6 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O95452
Clone Names 2052003
Peptide ID 2052003
Additional Information
Gene ID 10804
Other Names Gap junction beta-6 protein, Connexin-30, Cx30, GJB6
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1546a was selected from the N-term region of human GJB6. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GJB6
Function One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Cellular Location Cell membrane; Multi-pass membrane protein. Cell junction, gap junction
Research Areas
Citations (0)

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Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. I Mutations in GJB2 are associated with genetically derived hearing impairments, including autosomal dominant, bilateral, middle to high frequency hearing loss.


Beltramello, M., et al., Biochem. Biophys. Res. Commun. 305(4):1024-1033 (2003).Common, J.E., et al., Biochem. Biophys. Res. Commun. 298(5):651-656 (2002).Smith, F.J., et al., J. Invest. Dermatol. 118(3):530-532 (2002).del Castillo, I., et al., N. Engl. J. Med. 346(4):243-249 (2002).Pallares-Ruiz, N., et al., Eur. J. Hum. Genet. 10(1):72-76 (2002).

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$ 80.00
Cat# BP1546a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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