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Hippocalcin Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P84074
Other Accession P32076
Clone Names 2010210
Additional Information
Gene ID 3208
Other Names Neuron-specific calcium-binding protein hippocalcin, Calcium-binding protein BDR-2, HPCA, BDR2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1564c was selected from the Center region of human Hippocalcin . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HPCA
Synonyms BDR2
Function May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds two calcium ions.
Tissue Location Brain specific..
Research Areas
Citations (0)

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Background

Hippocalcin is a member of neuron-specific calcium-binding proteins family found in the retina and brain. This protein is associated with the plasma membrane. It has similarities to proteins located in the photoreceptor cells that regulate photosignal transduction in a calcium-sensitive manner. This protein displays recoverin activity and a calcium-dependent inhibition of rhodopsin kinase. It is identical to the rat and mouse hippocalcin proteins and thought to play an important role in neurons of the central nervous system in a number of species.

References

Takamatsu, K., et al., Biochem. Biophys. Res. Commun. 200(1):606-611 (1994).Hidaka, H., et al., Neurosci. Res. 16(2):73-77 (1993).Kobayashi, M., et al., Biochem. Biophys. Res. Commun. 189(1):511-517 (1992).Masaki, T., et al., Gene 225 (1-2), 117-124 (1998).Ivings, L., et al., Biochem. J. 363 (Pt 3), 599-608 (2002).

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$ 80.00
Cat# BP1564c
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