|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP1570a was selected from the N-term region of human Calmodulin . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Calmodulin is the archetype of the family of calcium-modulated proteins of which nearly 20 members have been found. They are identified by their occurrence in the cytosol or on membranes facing the cytosol and by a high affinity for calcium. Calmodulin contains 149 amino acids and has 4 calcium-binding domains. Its functions include roles in growth and the cell cycle as well as in signal transduction and the synthesis and release of neurotransmitters.
Radding, W., et al., AIDS Res. Hum. Retroviruses 16(15):1519-1525 (2000).Wang, D., et al., J. Neurochem. 75(2):763-771 (2000).Toutenhoofd, S.L., et al., Cell Calcium 23(5):323-338 (1998).Matoba, R., et al., Gene 146(2):199-207 (1994).Berchtold, M.W., et al., Genomics 16(2):461-465 (1993).
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