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KChIP1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9NZI2
Clone Names 2010408
Additional Information
Gene ID 30820
Other Names Kv channel-interacting protein 1, KChIP1, A-type potassium channel modulatory protein 1, Potassium channel-interacting protein 1, Vesicle APC-binding protein, KCNIP1, KCHIP1, VABP
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1571b was selected from the C-term region of human KChIP1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KCHIP1, VABP
Function Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Regulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND1/Kv4.1 and KCND2/Kv4.2 currents. Increases the presence of KCND2 at the cell surface.
Cellular Location Cell membrane; Peripheral membrane protein Cytoplasm. Cell projection, dendrite {ECO:0000250|UniProtKB:Q8R426}
Tissue Location Isoform 1 and isoform 2 are expressed in brain and kidney. Isoform 1 is also expressed in liver, pancreas, skeletal muscle, small intestine and testis. Isoform 2 is also expressed in lung, pancreas, leukocytes, prostate and thymus
Research Areas
Citations (0)

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KChIP1 is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium.


Bahring, R., et al., J. Biol. Chem. 276(26):23888-23894 (2001).An, W.F., et al., Nature 403(6769):553-556 (2000).

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$ 80.00
Cat# BP1571b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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