|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP1573f was selected from the C-term region of human Mouse KChIP2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
KChIP2b is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium.
Kim, L.A., et al., J. Biol. Chem. 279(7):5549-5554 (2004). Ren, X., et al., J. Biol. Chem. 278(44):43564-43570 (2003). Deschenes, I., et al., Circulation 106(4):423-429 (2002). Ohya, S., et al., Biochem. Biophys. Res. Commun. 282(1):96-102 (2001). Bahring, R., et al., J. Biol. Chem. 276(26):23888-23894 (2001).
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