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Mouse Cabc1 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q60936
Clone Names 110316063
Peptide ID 110316063
Additional Information
Gene ID 67426
Other Names Chaperone activity of bc1 complex-like, mitochondrial, Chaperone-ABC1-like, 2711-, aarF domain-containing protein kinase 3, Adck3, Cabc1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Coq8a {ECO:0000250|UniProtKB:Q8NI60}
Function Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:27499294). Its substrate specificity is unclear: does not show any protein kinase activity (PubMed:27499294). Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway, as suggested by its ability to bind coenzyme Q lipid intermediates (By similarity). Shows an unusual selectivity for binding ADP over ATP (By similarity).
Cellular Location Mitochondrion {ECO:0000250|UniProtKB:Q8NI60}. Membrane; Single- pass membrane protein {ECO:0000250|UniProtKB:Q8NI60, ECO:0000255}
Tissue Location Present in various tissues (at protein level).
Research Areas
Citations (0)

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Background

Cabc1 may be a chaperone-like protein essential for the proper conformation and functioning of protein complexes in the respiratory chain.

References

Pagliarini, D.J., et al. Cell 134(1):112-123(2008)Garcia-Frigola, C., et al. Brain Res. Mol. Brain Res. 122(2):133-150(2004)

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$ 80.00
Cat# BP16067c
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