PMP22 Antibody Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q01453 |
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Clone Names | 110518004 |
Gene ID | 5376 |
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Other Names | Peripheral myelin protein 22, PMP-22, Growth arrest-specific protein 3, GAS-3, PMP22, GAS3 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PMP22 |
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Synonyms | GAS3 |
Function | Might be involved in growth regulation, and in myelinization in the peripheral nervous system. |
Cellular Location | Cell membrane; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes an integral membrane protein that is amajor component of myelin in the peripheral nervous system. Variousmutations of this gene are causes of Charcot-Marie-Tooth diseaseType IA, Dejerine-Sottas syndrome, and hereditary neuropathy withliability to pressure palsies.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Kohl, B., et al. Am. J. Pathol. 176(3):1390-1399(2010)Kabzinska, D., et al. J. Appl. Genet. 51(2):203-209(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Stangler Herodez, S., et al. J. Int. Med. Res. 37(5):1626-1631(2009)
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