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TSLP Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q969D9 |
|---|---|
| Clone Names | 100507294 |
| Gene ID | 85480 |
|---|---|
| Other Names | Thymic stromal lymphopoietin, TSLP |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | TSLP |
|---|---|
| Function | [Isoform 1]: Cytokine that induces the release of T-cell- attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. |
| Cellular Location | Secreted. |
| Tissue Location | Isoform 1 is expressed in a number of tissues including heart, liver and prostate. Isoform 2 is the predominant form in keratinocytes of oral mucosa, skin and in salivary glands. It is secreted into saliva. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a hemopoietic cytokine proposed tosignal through a heterodimeric receptor complex composed of thethymic stromal lymphopoietin receptor and the IL-7R alpha chain. Itmainly impacts myeloid cells and induces the release of Tcell-attracting chemokines from monocytes and enhances thematuration of CD11c(+) dendritic cells. Alternative splicing ofthis gene results in two transcript variants.
References
Hunninghake, G.M., et al. Allergy 65(12):1566-1575(2010)Angelova-Fischer, I., et al. J. Invest. Dermatol. 130(10):2505-2507(2010)Smelter, D.F., et al. J. Immunol. 185(5):3035-3040(2010)Wu, W.H., et al. J. Allergy Clin. Immunol. 126(2):290-299(2010)Harada, M., et al. Am. J. Respir. Cell Mol. Biol. (2010) In press :
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