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LOC388630 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession A6NFA1
Other Accession NP_001181915.1
Clone Names 100408038
Peptide ID 100408038
Additional Information
Gene ID 388630
Other Names Metalloprotease TIKI2, 34--, Heart, kidney and adipose-enriched transmembrane protein homolog, TRAB domain-containing protein 2B, TRABD2B, HKAT, TIKI2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms HKAT, TIKI2
Function Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N- terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation.
Cellular Location Cell membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

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$ 80.00
Cat# BP16114b
(40 western blots)
Availability: In Stock
Bulk Size
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