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LOC388630 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | A6NFA1 |
|---|---|
| Other Accession | NP_001181915.1 |
| Clone Names | 100408038 |
| Gene ID | 388630 |
|---|---|
| Other Names | Metalloprotease TIKI2, 34--, Heart, kidney and adipose-enriched transmembrane protein homolog, TRAB domain-containing protein 2B, TRABD2B, HKAT, TIKI2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | TRABD2B |
|---|---|
| Synonyms | HKAT, TIKI2 |
| Function | Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
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$ 277.78
Cat# BP16114b
Ordering Information
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