|Other Names||Delta-sarcoglycan, Delta-SG, 35 kDa dystrophin-associated glycoprotein, 35DAG, SGCD|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.|
|Cellular Location||Cell membrane, sarcolemma; Single-pass type II membrane protein. Cytoplasm, cytoskeleton|
|Tissue Location||Most strongly expressed in skeletal and cardiac muscle. Also detected in smooth muscle. Weak expression in brain and lung|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is one of the four knowncomponents of the sarcoglycan complex, which is a subcomplex of thedystrophin-glycoprotein complex (DGC). DGC forms a link between theF-actin cytoskeleton and the extracellular matrix. This protein isexpressed most abundantly in skeletal and cardiac muscle. Mutationsin this gene have been associated with autosomal recessivelimb-girdle muscular dystrophy and dilated cardiomyopathy.Alternatively spliced transcript variants encoding distinctisoforms have been observed for this gene.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Zimmerman, R.S., et al. Genet. Med. 12(5):268-278(2010)Ordonez-Razo, R.M., et al. Genet Test Mol Biomarkers 14(2):237-240(2010)Lin, W.Y., et al. BMC Res Notes 3, 26 (2010) :
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