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NUDT2 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P50583 |
|---|---|
| Clone Names | 100528195 |
| Gene ID | 318 |
|---|---|
| Other Names | Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical], Diadenosine 5', 5'''-P1, P4-tetraphosphate asymmetrical hydrolase, Ap4A hydrolase, Ap4Aase, Diadenosine tetraphosphatase, Nucleoside diphosphate-linked moiety X motif 2, Nudix motif 2, NUDT2, APAH1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | NUDT2 |
|---|---|
| Synonyms | APAH1 |
| Function | Catalyzes the asymmetric hydrolysis of diadenosine 5',5'''- P1,P4-tetraphosphate (Ap4A) to yield AMP and ATP (By similarity). Exhibits decapping activity towards FAD-capped RNAs and dpCoA-capped RNAs in vitro (By similarity). |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the MutT family ofnucleotide pyrophosphatases, a subset of the larger NUDIX hydrolasefamily. The gene product possesses a modification of the MutTsequence motif found in certain nucleotide pyrophosphatases. Theenzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and isresponsible for maintaining the intracellular level of thedinucleotide Ap4A, the function of which has yet to be established.This gene may be a candidate tumor suppressor gene. Alternativesplicing has been observed at this locus and three transcriptvariants, all encoding the same protein, have been identified.
References
Vasilenko, N., et al. Virol. J. 7, 31 (2010) :Swarbrick, J.D., et al. J. Biol. Chem. 280(9):8471-8481(2005)Swarbrick, J.D., et al. J. Biomol. NMR 31(2):181-182(2005)Pitcher, W.H. III, et al. Antiviral Res. 58(3):227-233(2003)Guranowski, A., et al. Acta Biochim. Pol. 50(1):123-130(2003)
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