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RPLP0 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P05388 |
|---|---|
| Clone Names | 100311234 |
| Gene ID | 6175 |
|---|---|
| Other Names | 60S acidic ribosomal protein P0, 60S ribosomal protein L10E, RPLP0 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | RPLP0 |
|---|---|
| Function | Ribosomal protein P0 is the functional equivalent of E.coli protein L10. |
| Cellular Location | Nucleus. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs (PubMed:19188445, PubMed:17289661). |
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Provided below are standard protocols that you may find useful for product applications.
Background
Ribosomes, the organelles that catalyze protein synthesis,consist of a small 40S subunit and a large 60S subunit. Togetherthese subunits are composed of 4 RNA species and approximately 80structurally distinct proteins. This gene encodes a ribosomalprotein that is a component of the 60S subunit. The protein, whichis the functional equivalent of the E. coli L10 ribosomal protein,belongs to the L10P family of ribosomal proteins. It is a neutralphosphoprotein with a C-terminal end that is nearly identical tothe C-terminal ends of the acidic ribosomal phosphoproteins P1 andP2. The P0 protein can interact with P1 and P2 to form a pentamericcomplex consisting of P1 and P2 dimers, and a P0 monomer. Theprotein is located in the cytoplasm. Transcript variants derivedfrom alternative splicing exist; they encode the same protein. Asis typical for genes encoding ribosomal proteins, there aremultiple processed pseudogenes of this gene dispersed through thegenome.
References
Vascotto, C., et al. Mol. Cell. Biol. 29(7):1834-1854(2009)Rinne, T., et al. Hum. Mol. Genet. 17(13):1968-1977(2008)Chang, T.W., et al. Oncogene 27(3):332-338(2008)Rikova, K., et al. Cell 131(6):1190-1203(2007)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
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