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CENPC1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q03188
Clone Names 100528041
Peptide ID 100528041
Additional Information
Gene ID 1060
Other Names Centromere protein C, CENP-C, Centromere autoantigen C, Centromere protein C 1, CENP-C 1, Interphase centromere complex protein 7, CENPC, CENPC1, ICEN7
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CENPC1, ICEN7
Function Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions.
Cellular Location Nucleus. Chromosome, centromere, kinetochore Note=Localizes exclusively in the kinetochore domain of centromeres.
Research Areas
Citations (0)

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Centromere protein C 1 is a centromere autoantigen and acomponent of the inner kinetochore plate. The protein is requiredfor maintaining proper kinetochore size and a timely transition toanaphase. A putative pseudogene exists on chromosome 12. [providedby RefSeq].


Gopalakrishnan, S., et al. Hum. Mol. Genet. 18(17):3178-3193(2009)Yosifova, A., et al. J Affect Disord 117 (1-2), 87-97 (2009) :Baranzini, S.E., et al. Hum. Mol. Genet. 18(4):767-778(2009)Trazzi, S., et al. PLoS ONE 4 (6), E5832 (2009) :Seshadri, S., et al. BMC Med. Genet. 8 SUPPL 1, S15 (2007) :

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$ 80.00
Cat# BP16246c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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