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UGT1A10 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9HAW8
Clone Names 100311265
Peptide ID 100311265
Additional Information
Gene ID 54575
Other Names UDP-glucuronosyltransferase 1-10, UDPGT 1-10, UGT1*10, UGT1-10, UGT110, UDP-glucuronosyltransferase 1-J, UGT-1J, UGT1J, UDP-glucuronosyltransferase 1A10, UGT1A10, GNT1, UGT1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name UGT1A10
Synonyms GNT1, UGT1
Function UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1.
Cellular Location Microsome. Endoplasmic reticulum membrane; Single-pass membrane protein
Tissue Location Liver and colon. Isoform 1 and isoform 2 are expressed in colon, esophagus and small intestine; isoform 2 but not isoform 1 is expressed in liver or kidney (PubMed:18004212)
Research Areas
Citations (0)

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UGT1A10 is a UDP-glucuronosyltransferase, an enzymeof the glucuronidation pathway that transforms small lipophilicmolecules, such as steroids, bilirubin, hormones, and drugs, intowater-soluble, excretable metabolites. This gene is part of acomplex locus that encodes several UDP-glucuronosyltransferases.The locus includes thirteen unique alternate first exons followedby four common exons. Four of the alternate first exons areconsidered pseudogenes. Each of the remaining nine 5' exons may bespliced to the four common exons, resulting in nine proteins withdifferent N-termini and identical C-termini. Each first exonencodes the substrate binding site, and is regulated by its ownpromoter. The enzyme encoded by this gene has glucuronidaseactivity on mycophenolic acid, coumarins, and quinolines. [providedby RefSeq].


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Mick, E., et al. J Am Acad Child Adolesc Psychiatry 49(9):898-905(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Tang, L., et al. Mol. Pharm. 7(3):664-679(2010)Itaaho, K., et al. Drug Metab. Dispos. 38(4):687-696(2010)

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$ 80.00
Cat# BP16269a
Availability: In Stock
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