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VSX1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9NZR4
Clone Names 100318257
Peptide ID 100318257
Additional Information
Gene ID 30813
Other Names Visual system homeobox 1, Homeodomain protein RINX, Retinal inner nuclear layer homeobox protein, Transcription factor VSX1, VSX1, RINX
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name VSX1
Synonyms RINX
Function Binds to the 37-bp core of the locus control region (LCR) of the red/green visual pigment gene cluster. May regulate the activity of the LCR and the cone opsin genes at earlier stages of development.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}
Tissue Location In the adult eye, expressed in lens, iris, ciliary body, choroid, optical nerve head and, most strongly, in retina, but not expressed in sclera and cornea. According to PubMed 11978762, expressed in adult retina but not in lens and cornea. Within adult retina, found exclusively in the inner nuclear layer. Isoform 1, isoform 2, isoform 3 and isoform 4 expressed in adult retina, but not in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle. Not expressed in thymus and spleen. Expressed in embryonic craniofacial tissue Expressed in fetal (week 14) retina. Strongly expressed in neonatal retina (day 0), weakly in neonatal lens (day 0), choroid (day 0) and cornea (day 0, 4; month 9)
Research Areas
Citations (0)

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VSX1 contains a paired-likehomeodomain and binds to the core of the locus control region ofthe red/green visual pigment gene cluster. The encoded protein mayregulate expression of the cone opsin genes early in development.Mutations in this gene can cause posterior polymorphous cornealdystrophy and keratoconus.


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Dash, D.P., et al. Eye (Lond) 24(6):1085-1092(2010)Stabuc-Silih, M., et al. Cornea 29(2):172-176(2010)Stabuc-Silih, M., et al. Acta Dermatovenerol Alp Panonica Adriat 19(2):3-10(2010)Paliwal, P., et al. Mol. Vis. 15, 2475-2479 (2009) :

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$ 80.00
Cat# BP16277c
(40 western blots)
Availability: In Stock
Bulk Size
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