|Other Names||Mitochondrial import inner membrane translocase subunit Tim21, TIM21-like protein, mitochondrial, TIMM21, C18orf55, TIM21|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Participates in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex. TIM21 probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes.|
|Cellular Location||Mitochondrion membrane; Single-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
C18orf55 may participate in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane (By similarity).
Gerhard, D.S., et al. Genome Res. 14 (10B), 2121-2127 (2004) :
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