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SFTPB Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P07988
Clone Names 100427199
Peptide ID 100427199
Additional Information
Gene ID 6439
Other Names Pulmonary surfactant-associated protein B, SP-B, 18 kDa pulmonary-surfactant protein, 6 kDa protein, Pulmonary surfactant-associated proteolipid SPL(Phe), SFTPB, SFTP3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms SFTP3
Function Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air- liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.
Cellular Location Secreted, extracellular space, surface film.
Research Areas
Citations (0)

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SFTPB is the pulmonary-associated surfactantprotein B (SPB), an amphipathic surfactant protein essential forlung function and homeostasis after birth. Pulmonary surfactant isa surface-active lipoprotein complex composed of 90% lipids and 10%proteins which include plasma proteins and apolipoproteins SPA,SPB, SPC and SPD. The surfactant is secreted by the alveolar cellsof the lung and maintains the stability of pulmonary tissue byreducing the surface tension of fluids that coat the lung. The SPBenhances the rate of spreading and increases the stability ofsurfactant monolayers in vitro. Multiple mutations in this genehave been identified, which cause pulmonary surfactant metabolismdysfunction type 1, also called pulmonary alveolar proteinosis dueto surfactant protein B deficiency, and are associated with fatalrespiratory distress in the neonatal period. Alternatively splicedtranscript variants encoding the same protein have been identified.


Baekvad-Hansen, M., et al. Eur. Respir. J. (2010) In press :Kim, W.J., et al. Eur. Respir. J. (2010) In press :Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010)Cho, M.H., et al. Respir. Res. 11, 30 (2010) :Chaiworapongsa, T., et al. J. Matern. Fetal. Neonatal. Med. 21(9):663-670(2008)

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$ 80.00
Cat# BP16320c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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