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TMOD1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P28289
Clone Names 100528148
Peptide ID 100528148
Additional Information
Gene ID 7111
Other Names Tropomodulin-1, Erythrocyte tropomodulin, E-Tmod, TMOD1, D9S57E, TMOD
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TMOD1
Synonyms D9S57E, TMOD
Function Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus.
Cellular Location Cytoplasm, cytoskeleton. Note=In myofibrils with sarcomeric structure, localizes to the pointed end of actin thin filaments (PubMed:25250574).
Tissue Location Highly expressed in the erythrocyte, heart and skeletal muscle
Research Areas
Citations (0)

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TMOD1 is a member of the tropomodulin family. Theencoded protein is an actin-capping protein that regulatestropomyosin by binding to its N-terminus, inhibitingdepolymerization and elongation of the pointed end of actinfilaments and thereby influencing the structure of the erythrocytemembrane skeleton. Multiple transcript variants encoding the sameprotein have been found for this gene.


Olsen, J.V., et al. Cell 127(3):635-648(2006)Kong, K.Y., et al. J. Biol. Chem. 281(14):9589-9599(2006)Vera, C., et al. Arch. Biochem. Biophys. 444(2):130-138(2005)Pawlak, G., et al. Int. J. Cancer 110(3):368-373(2004)Rho, S.B., et al. FEBS Lett. 557 (1-3), 57-63 (2004) :

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$ 80.00
Cat# BP16327c
(40 western blots)
Availability: In Stock
Bulk Size
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