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LMAN2 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q12907 |
|---|---|
| Clone Names | 100528204 |
| Gene ID | 10960 |
|---|---|
| Other Names | Vesicular integral-membrane protein VIP36, Glycoprotein GP36b, Lectin mannose-binding 2, Vesicular integral-membrane protein 36, VIP36, LMAN2, C5orf8 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | LMAN2 |
|---|---|
| Synonyms | C5orf8 |
| Function | Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high- mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans (By similarity). |
| Cellular Location | Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein |
| Tissue Location | Ubiquitous. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
LMAN2 is a type I transmembrane lectin thatshuttles between the endoplasmic reticulum, the Golgi apparatus andthe plasma membrane. The encoded protein binds high mannose typeglycoproteins and may facilitate their sorting, trafficking andquality control.
References
Reiterer, V., et al. Traffic 11(8):1044-1055(2010)Kottgen, A., et al. Nat. Genet. 42(5):376-384(2010)Nawa, D., et al. Glycobiology 17(9):913-921(2007)Kawasaki, N., et al. J. Biochem. 141(2):221-229(2007)Kamiya, Y., et al. J. Biol. Chem. 280(44):37178-37182(2005)
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