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ELL2 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O00472
Clone Names 100416021
Peptide ID 100416021
Additional Information
Gene ID 22936
Other Names RNA polymerase II elongation factor ELL2, ELL2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ELL2
Function Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968). Plays a role in immunoglobulin secretion in plasma cells: directs efficient alternative mRNA processing, influencing both proximal poly(A) site choice and exon skipping, as well as immunoglobulin heavy chain (IgH) alternative processing. Probably acts by regulating histone modifications accompanying transition from membrane- specific to secretory IgH mRNA expression.
Cellular Location Nucleus.
Research Areas
Citations (0)

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Elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA.


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Martincic, K., et al. Nat. Immunol. 10(10):1102-1109(2009)Simone, F., et al. Blood 101(6):2355-2362(2003)Simone, F., et al. Blood 98(1):201-209(2001)Shilatifard, A., et al. Proc. Natl. Acad. Sci. U.S.A. 94(8):3639-3643(1997)

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$ 80.00
Cat# BP16355b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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