|Other Names||LIM and senescent cell antigen-like-containing domain protein 2, Particularly interesting new Cys-His protein 2, PINCH-2, Lims2, Pinch2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors.|
|Cellular Location||Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side|
|Tissue Location||Detected in heart, lung, kidney, liver, urinary bladder, fat, skin, skeletal muscle, uterus, large intestine and testis.|
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Provided below are standard protocols that you may find useful for product applications.
Competes with LIMS1 for binding to ILK. Plays a role in modulating cell spreading and migration (By similarity).
Guo, G., et al. Dev. Cell 18(4):675-685(2010)Liang, X., et al. Circulation 120(7):568-576(2009)Pereira, J.A., et al. J. Cell Biol. 185(1):147-161(2009)Aguado, T., et al. J. Neurosci. 26(5):1551-1561(2006)Stanchi, F., et al. J. Cell. Sci. 118 (PT 24), 5899-5910 (2005) :
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