MNX1 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P50219 |
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Clone Names | 100528119 |
Gene ID | 3110 |
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Other Names | Motor neuron and pancreas homeobox protein 1, Homeobox protein HB9, MNX1, HLXB9 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | MNX1 |
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Synonyms | HLXB9 |
Function | Transcription factor (By similarity). Recognizes and binds to the regulatory elements of target genes, such as visual system homeobox CHX10, negatively modulating transcription (By similarity). Plays a role in establishing motor neuron identity, in concert with LIM domain transcription factor LMO4 (By similarity). Involved in negatively modulating transcription of interneuron genes in motor neurons, acting, at least in part, by blocking regulatory sequence interactions of the ISL1-LHX3 complex (By similarity). Involved in pancreas development and function; may play a role in pancreatic cell fate specification (By similarity). |
Cellular Location | Nucleus. |
Tissue Location | Expressed in lymphoid and pancreatic tissues. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a nuclear protein, which contains ahomeobox domain and is a transcription factor. Mutations in thisgene result in Currarino syndrome, an autosomic dominant congenitalmalformation. Alternatively spliced transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].
References
Turgut, M. Acta Neurochir (Wien) 152(6):1083-1084(2010)Garcia-Barcelo, M.M., et al. J. Pediatr. Surg. 44(10):1892-1898(2009)Park, J., et al. Cancer Genet. Cytogenet. 191(2):102-105(2009)Ballabio, E., et al. Leukemia 23(6):1179-1182(2009)Taketani, T., et al. Cancer Genet. Cytogenet. 186(2):115-119(2008)
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