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MTA3 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9BTC8
Clone Names 100528219
Peptide ID 100528219
Additional Information
Gene ID 57504
Other Names Metastasis-associated protein MTA3, MTA3, KIAA1266
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MTA3
Synonyms KIAA1266
Function Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00512, ECO:0000255|PROSITE-ProRule:PRU00624, ECO:0000269|PubMed:12705869}
Tissue Location Expressed in germinal centers of lymphoid tissues. No expression in nonepithelial cells
Research Areas
Citations (0)

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Background

MTA3 plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels.

References

Bruning, A., et al. Histochem. Cell Biol. 132(1):33-38(2009)Lasky-Su, J., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (8), 1345-1354 (2008) :Zhang, H., et al. Genes Dev. 20(21):2943-2948(2006)Yu, J.C., et al. J. Biomed. Sci. 13(3):419-432(2006)Fujita, N., et al. Cell 119(1):75-86(2004)

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$ 80.00
Cat# BP16492b
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