|Other Names||Ras-related protein Rab-41, RAB41|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Required for normal Golgi ribbon organization and ER-to- Golgi trafficking.|
|Cellular Location||Cytoplasm. Note=punctate localization concentrated in ruffled regions at the cell periphery|
|Tissue Location||Widely expressed in brain, testis, lung, heart, ovary, colon, kidney, uterus and spleen but not in liver|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a small GTP-binding protein that belongsto the largest family within the Ras superfamily. These proteinsfunction as regulators of membrane trafficking. They cycle betweeninactive GDP-bound and activated GTP-bound states, which iscontrolled by GTP hydrolysis-activating proteins (GAPs). Thisfamily member can be activated by the GAP protein RN-Tre, and it islocalized to the Golgi complex.
Haas, A.K., et al. Nat. Cell Biol. 7(9):887-893(2005)Pereira-Leal, J.B., et al. J. Mol. Biol. 313(4):889-901(2001)
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