RAB41 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q5JT25 |
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Clone Names | 100422181 |
Gene ID | 347517 |
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Other Names | Ras-related protein Rab-41, RAB41 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | RAB41 |
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Function | Required for normal Golgi ribbon organization and ER-to-Golgi trafficking. |
Cellular Location | Cytoplasm. Note=punctate localization concentrated in ruffled regions at the cell periphery |
Tissue Location | Widely expressed in brain, testis, lung, heart, ovary, colon, kidney, uterus and spleen but not in liver |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a small GTP-binding protein that belongsto the largest family within the Ras superfamily. These proteinsfunction as regulators of membrane trafficking. They cycle betweeninactive GDP-bound and activated GTP-bound states, which iscontrolled by GTP hydrolysis-activating proteins (GAPs). Thisfamily member can be activated by the GAP protein RN-Tre, and it islocalized to the Golgi complex.
References
Haas, A.K., et al. Nat. Cell Biol. 7(9):887-893(2005)Pereira-Leal, J.B., et al. J. Mol. Biol. 313(4):889-901(2001)
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