|Other Names||Tether containing UBX domain for GLUT4, Alveolar soft part sarcoma chromosomal region candidate gene 1 protein, Alveolar soft part sarcoma locus, Renal papillary cell carcinoma protein 17, UBX domain-containing protein 9, ASPSCR1, ASPL, RCC17, TUG, UBXD9, UBXN9|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||ASPL, RCC17, TUG, UBXD9, UBXN9|
|Function||Tethering protein that sequesters GLUT4-containing vesicles in the cytoplasm in the absence of insulin. Modulates the amount of GLUT4 that is available at the cell surface (By similarity). Enhances VCP methylation catalyzed by VCPKMT.|
|Cellular Location||Endomembrane system; Peripheral membrane protein. Endoplasmic reticulum- Golgi intermediate compartment membrane; Peripheral membrane protein Cytoplasm. Nucleus|
|Tissue Location||Ubiquitous. Highly expressed in testis, heart, skeletal muscle and pancreas.|
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Provided below are standard protocols that you may find useful for product applications.
This gene is a candidate gene for alveolar soft partsarcoma (ASPS). It has been found that this gene is fused withtranscription factor TFE3 gene in ASPS and also in renal cellcarcinomas. Several alternatively spliced transcript variants ofthis gene have been described, but their full length nature has notbeen determined.
Ban, H.J., et al. BMC Genet. 11, 26 (2010) :Alexandru, G., et al. Cell 134(5):804-816(2008)Vistica, D.T., et al. J. Pediatr. Hematol. Oncol. 30(1):46-52(2008)Olsen, J.V., et al. Cell 127(3):635-648(2006)Bogan, J.S., et al. Nature 425(6959):727-733(2003)
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