|Other Names||Zinc finger CCCH domain-containing protein 14, Mammalian suppressor of tau pathology-2, MSUT-2, Renal carcinoma antigen NY-REN-37, ZC3H14|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides.|
|Cellular Location||Nucleus speckle Isoform 3: Nucleus speckle.|
|Tissue Location||Isoform 1 and isoform 6 are expressed in fetal and adult brain. Isoform 1 and isoform 6 are expressed in fetal and adult temporal lobe.|
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Provided below are standard protocols that you may find useful for product applications.
ZC3H14 belongs to a family of poly(A)-binding proteinsthat influence gene expression by regulating mRNA stability,nuclear export, and translation (Kelly et al., 2007 [PubMed17630287]).
Wheeler, J.M., et al. Biochem. Soc. Trans. 38(4):973-976(2010)Leung, S.W., et al. Gene 439 (1-2), 71-78 (2009) :Kelly, S.M., et al. Proc. Natl. Acad. Sci. U.S.A. 104(30):12306-12311(2007)Scanlan, M.J., et al. Int. J. Cancer 83(4):456-464(1999)
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