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GPKOW Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q92917
Clone Names 100603230
Additional Information
Gene ID 27238
Other Names G patch domain and KOW motifs-containing protein, G patch domain-containing protein 5, Protein MOS2 homolog, Protein T54, GPKOW, GPATC5, GPATCH5, T54
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GPKOW
Synonyms GPATC5, GPATCH5, T54
Function RNA-binding protein involved in pre-mRNA splicing. As a component of the minor spliceosome, involved in the splicing of U12- type introns in pre-mRNAs (Probable).
Cellular Location Nucleus
Research Areas
Citations (0)
citation

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Background

T54, also known as GPKOW (G patch domain and KOW motifs), GPATC5 or GPATCH5 (G patch domain-containing protein 5), is a potential RNA-binding protein consisting of one central G patch domain and two C-terminal KOW domains. T54 is a 476 amino acid protein belonging to the MOS2 family. It is a mammalian homolog of the Arabidopsis thaliana MOS2 (modifier of SNC1, 2) nuclear protein that is required for innate immunity. Similar to A. thaliana MOS2, T54 localizes to the nucleus and contains G patch and KOW domains, suggesting that T54 may play a similar role in mammalian innate immunity.

References

Lamesch, P., et al. Genomics 89(3):307-315(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)Zhang, Y., et al. Curr. Biol. 15(21):1936-1942(2005)Schindelhauer, D., et al. Genome Res. 6(11):1056-1069(1996)

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$ 277.78
Cat# BP16513c
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