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ARNT2 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9HBZ2
Clone Names 100617188
Peptide ID 100617188
Additional Information
Gene ID 9915
Other Names Aryl hydrocarbon receptor nuclear translocator 2, ARNT protein 2, Class E basic helix-loop-helix protein 1, bHLHe1, ARNT2, BHLHE1, KIAA0307
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ARNT2
Synonyms BHLHE1, KIAA0307
Function Transcription factor that plays a role in the development of the hypothalamo-pituitary axis, postnatal brain growth, and visual and renal function (PubMed:24022475). Specifically recognizes the xenobiotic response element (XRE).
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981}
Research Areas
Citations (0)

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This gene encodes a member of thebasic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily oftranscription factors. The encoded protein acts as a partner forseveral sensor proteins of the bHLH-PAS family, formingheterodimers with the sensor proteins that bind regulatory DNAsequences in genes responsive to developmental and environmentalstimuli. Under hypoxic conditions, the encoded protein complexeswith hypoxia-inducible factor 1alpha in the nucleus and thiscomplex binds to hypoxia-responsive elements in enhancers andpromoters of oxygen-responsive genes. A highly similar protein inmouse forms functional complexes with both aryl hydrocarbonreceptors and Single-minded proteins, suggesting addition roles forthe encoded protein in the metabolism of xenobiotic compounds andthe regulation of neurogenesis, respectively.


Ramirez, J.M., et al. Eur. J. Immunol. 40(9):2450-2459(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :Chakrabarti, B., et al. Autism Res 2(3):157-177(2009)Ferreira, M.A., et al. Nat. Genet. 40(9):1056-1058(2008)Martinez, V., et al. Breast Cancer Res. Treat. 110(3):521-530(2008)

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$ 80.00
Cat# BP16544c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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