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FHOD1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9Y613
Clone Names 100318089
Peptide ID 100318089
Additional Information
Gene ID 29109
Other Names FH1/FH2 domain-containing protein 1, Formin homolog overexpressed in spleen 1, FHOS, Formin homology 2 domain-containing protein 1, FHOD1, FHOS, FHOS1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name FHOD1
Synonyms FHOS, FHOS1
Function Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. Acts synergistically with ROCK1 to promote SRC-dependent non-apoptotic plasma membrane blebbing.
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, bleb. Note=Predominantly cytoplasmic
Tissue Location Ubiquitous. Highly expressed in spleen.
Research Areas
Citations (0)

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This gene encodes a protein which is a member of theformin/diaphanous family of proteins. The gene is ubiquitouslyexpressed but is found in abundance in the spleen. The encodedprotein has sequence homology to diaphanous and formin proteinswithin the Formin Homology (FH)1 and FH2 domains. It also containsa coiled-coil domain, a collagen-like domain, two nuclearlocalization signals, and several potential PKC and PKAphosphorylation sites. It is a predominantly cytoplasmic proteinand is expressed in a variety of human cell lines. [provided byRefSeq].


Hannemann, S., et al. J. Biol. Chem. 283(41):27891-27903(2008)Schulte, A., et al. Structure 16(9):1313-1323(2008)Takeya, R., et al. EMBO J. 27(4):618-628(2008)Schulte, A., et al. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 63 (PT 10), 878-881 (2007) :Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)

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$ 80.00
Cat# BP16586b
Availability: In Stock
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