Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
DNALI1 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O14645 |
|---|---|
| Clone Names | 100603189 |
| Gene ID | 7802 |
|---|---|
| Other Names | Axonemal dynein light intermediate polypeptide 1, Inner dynein arm light chain, axonemal, hp28, DNALI1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | DNALI1 (HGNC:14353) |
|---|---|
| Function | Involved in sperm flagellum assembly. |
| Cellular Location | Cell projection, cilium. Cell projection, cilium, flagellum. Dynein axonemal particle {ECO:0000250|UniProtKB:Q6GN86}. Cytoplasm |
| Tissue Location | Expressed in many tissues. A smaller 0.9 kb and a larger 2.5 kb transcripts were detected at the highest level in the testis, at medium levels in the prostate, heart, liver, lung and pancreas, at low levels in the ovary, skeletal muscle and small intestine. Not detected in spleen, colon epithelium, thymus or peripheral blood leukocytes. The 0.9 kb transcript is expressed at a 20-fold higher level than the 2.5 kb transcript in the testis Expressed in spermatozoa and airway epithelial cells (at protein level) (PubMed:31178125). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
This gene is the human homolog of the Chlamydomonas innerdynein arm gene, p28. The precise function of this gene is notknown, however, it is a potential candidate for immotile ciliasyndrome (ICS). Ultrastructural defects of the inner dynein armsare seen in patients with ICS. Immotile mutant strains ofChlamydomonas, a biflagellated algae, exhibit similar defects.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Lamesch, P., et al. Genomics 89(3):307-315(2007)Combs, J., et al. Proc. Natl. Acad. Sci. U.S.A. 103(40):14883-14888(2006)Kastury, K., et al. J. Clin. Endocrinol. Metab. 82(9):3047-3053(1997)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
