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PRODH2 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9UF12 |
|---|---|
| Clone Names | 100422238 |
| Gene ID | 58510 |
|---|---|
| Other Names | Probable proline dehydrogenase 2, Kidney and liver proline oxidase 1, HsPOX1, Probable proline oxidase 2, PRODH2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PRODH2 (HGNC:17325) |
|---|---|
| Function | Dehydrogenase that converts trans-4-L-hydroxyproline to delta-1-pyrroline-3-hydroxy-5-carboxylate (Hyp) using ubiquinone-10 as the terminal electron acceptor. Can also use proline as a substrate but with a very much lower efficiency. Does not react with other diastereomers of Hyp: trans-4-D-hydroxyproline and cis-4-L- hydroxyproline. Ubiquininone analogs such as menadione, duroquinone and ubiquinone-1 react more efficiently than oxygen as the terminal electron acceptor during catalysis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is similar to prolinedehydrogenase (oxidase) 1, a mitochondrial enzyme which catalyzesthe first step in proline catabolism. The function of this proteinhas not been determined.
References
Cooper, S.K., et al. J. Biol. Chem. 283(16):10485-10492(2008)
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