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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   TMEM120B Antibody (C-term) Blocking Peptide   

TMEM120B Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession A0PK00
Clone Names 100422268
Peptide ID 100422268
Additional Information
Gene ID 144404
Other Names Transmembrane protein 120B, TMEM120B
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TMEM120B
Cellular Location Membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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TMEM120B (Transmembrane protein 120B) is a 339 amino acid multi-pass membrane protein that is encoded by a gene that maps to human chromosome 12. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy.


Rose, J. Phd, et al. Mol. Med. (2010) In press :Trynka, G., et al. Gut 58(8):1078-1083(2009)

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$ 80.00
Cat# BP16628b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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