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BCAS1 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession O75363
Clone Names 100528324
Peptide ID 100528324
Additional Information
Other Names Breast carcinoma-amplified sequence 1, Amplified and overexpressed in breast cancer, Novel amplified in breast cancer 1, BCAS1, AIBC1, NABC1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name BCAS1
Synonyms AIBC1, NABC1
Cellular Location Cytoplasm.
Tissue Location Expressed in brain and prostate, and at lower levels in testis, intestine and colon. Overexpressed in most breast cancer cell lines and down-regulated in some colorectal tumors. EMBL; AF041260; AAC39896.1; -; mRNA EMBL; AC004501; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; AC005220; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; BC126346; AAI26347.1; -; mRNA EMBL; AI904532; -; NOT_ANNOTATED_CDS; mRNA EMBL; CR749643; CAH18437.1; -; mRNA CCDS; CCDS13444.1; -. [O75363-1] RefSeq; NP_003648.2; NM_003657.3. [O75363-1] UniGene; Hs.400556; - ProteinModelPortal; O75363; - BioGrid; 114107; 3 STRING; 9606.ENSP00000379290; - iPTMnet; O75363; - PhosphoSitePlus; O75363; - BioMuta; BCAS1; - MaxQB; O75363; - PaxDb; O75363; - PeptideAtlas; O75363; - PRIDE; O75363; - DNASU; 8537; - Ensembl; ENST00000395961; ENSP00000379290; ENSG00000064787. [O75363-1] GeneID; 8537; - KEGG; hsa:8537; - UCSC; uc002xws.3; human. [O75363-1] CTD; 8537; - DisGeNET; 8537; - GeneCards; BCAS1; - H-InvDB; HIX0015925; - HGNC; HGNC:974; BCAS1 HPA; CAB033558; - HPA; HPA051816; - HPA; HPA054745; - MIM; 602968; gene neXtProt; NX_O75363; - OpenTargets; ENSG00000064787; - PharmGKB; PA25284; - eggNOG; ENOG410IJ5W; Eukaryota eggNOG; ENOG41119UT; LUCA GeneTree; ENSGT00390000003167; - HOGENOM; HOG000232037; - HOVERGEN; HBG082347; - InParanoid; O75363; - OMA; TQGAAKN; - OrthoDB; EOG091G07RJ; - PhylomeDB; O75363; - TreeFam; TF335555; - BioCyc; ZFISH:ENSG00000064787-MONOMER; - ChiTaRS; BCAS1; human GeneWiki; BCAS1; - GenomeRNAi; 8537; - PRO; PR:O75363; - Proteomes; UP000005640; Chromosome 20 Bgee; ENSG00000064787; - CleanEx; HS_BCAS1; - ExpressionAtlas; O75363; baseline and differential Genevisible; O75363; HS GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell GO; GO:0070062; C:extracellular exosome; IDA:UniProtKB InterPro; IPR026115; NABC1 PANTHER; PTHR15016; PTHR15016; 1 1: Evidence at protein level; Alternative splicing; Complete proteome; Cytoplasm; Phosphoprotein; Polymorphism; Reference proteome CHAIN 1 584 Breast carcinoma-amplified sequence 1 /FTId=PRO_0000064859 MOD_RES 124 124 Phosphoserine {ECO:0000250|UniProtKB:Q3ZB98} MOD_RES 192 192 Phosphoserine {ECO:0000250|UniProtKB:Q3ZB98} MOD_RES 314 314 Phosphoserine {ECO:0000250|UniProtKB:Q3ZB98} MOD_RES 381 381 Phosphoserine {ECO:0000250|UniProtKB:Q80YN3} MOD_RES 399 399 Phosphoserine {ECO:0000250|UniProtKB:Q80YN3} MOD_RES 480 480 Phosphothreonine {ECO:0000250|UniProtKB:Q80YN3} MOD_RES 552 552 Phosphoserine {ECO:0000250|UniProtKB:Q3ZB98} VAR_SEQ 309 309 T -> TASKAESVCDGQAGQKTSEIQARGTKKKHLDSPRLG LAFRKFFRHK (in isoform 2) /FTId=VSP_018520 VAR_SEQ 381 394 Missing (in isoform 2) /FTId=VSP_018521 VAR_SEQ 451 472 Missing (in isoform 2) /FTId=VSP_018522 VAR_SEQ 584 584 K -> KYTGKCVFSHVKKKWPFQEWSY (in isoform 2). /FTId=VSP_018523 VARIANT 24 24 Q -> K (in dbSNP:rs394732) /FTId=VAR_026674 VARIANT 163 163 V -> A (in dbSNP:rs158551) /FTId=VAR_026675 VARIANT 255 255 G -> E (in dbSNP:rs6022903) /FTId=VAR_024251 VARIANT 472 472 Q -> H (in dbSNP:rs35575210) /FTId=VAR_050691 VARIANT 583 583 S -> P (in dbSNP:rs1055246) /FTId=VAR_026676 CONFLICT 361 361 G -> D (in Ref. 5; CAH18437) SEQUENCE 584 AA; 61709 MW; 22921C0B37129944 CRC64; MGNQMSVPQR VEDQENEPEA ETYQDNASAL NGVPVVVSTH TVQHLEEVDL GISVKTDNVA TSSPETTEIS AVADANGKNL GKEAKPEAPA AKSRFFLMLS RPVPGRTGDQ AADSSLGSVK LDVSSNKAPA NKDPSESWTL PVAAGPGQDT DKTPGHAPAQ DKVLSAARDP TLLPPETGGA GGEAPSKPKD SSFFDKFFKL DKGQEKVPGD SQQEAKRAEH QDKVDEVPGL SGQSDDVPAG KDIVDGKEKE GQELGTADCS VPGDPEGLET AKDDSQAAAI AENNNSIMSF FKTLVSPNKA ETKKDPEDTG AEKSPTTSAD LKSDKANFTS QETQGAGKNS KGCNPSGHTQ SVTTPEPAKE GTKEKSGPTS LPLGKLFWKK SVKEDSVPTG AEENVVCESP VEIIKSKEVE SALQTVDLNE GDAAPEPTEA KLKREESKPR TSLMAFLRQM SVKGDGGITH SEEINGKDSS CQTSDSTEKT ITPPEPEPTG APQKGKEGSS KDKKSAAEMN KQKSNKQEAK EPAQCTEQAT VDTNSLQNGD KLQKRPEKRQ QSLGGFFKGL GPKRMLDAQV QTDPVSIGPV GKSK
Research Areas
Citations (0)

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Background

This gene resides in a region at 20q13 which is amplifiedin a variety of tumor types and associated with more aggressivetumor phenotypes. Among the genes identified from this region, itwas found to be highly expressed in three amplified breast cancercell lines and in one breast tumor without amplification at20q13.2. However, this gene is not in the common region of maximalamplification and its expression was not detected in the breastcancer cell line MCF7, in which this region is highly amplified.Although not consistently expressed, this gene is a candidateoncogene.

References

Rose, J. Phd, et al. Mol. Med. (2010) In press :Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Burmester, J.K., et al. Hum. Hered. 57(4):172-178(2004)Beardsley, D.I., et al. Exp. Cell Res. 290(2):402-413(2003)Deloukas, P., et al. Nature 414(6866):865-871(2001)

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$ 80.00
Cat# BP16632a
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