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LEP Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P41159
Clone Names 110111010
Peptide ID 110111010
Additional Information
Gene ID 3952
Other Names Leptin, Obese protein, Obesity factor, LEP, OB, OBS
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name LEP
Synonyms OB, OBS
Function May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
Cellular Location Secreted.
Research Areas
Citations (0)

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This gene encodes a protein that is secreted by whiteadipocytes, and which plays a major role in the regulation of bodyweight. This protein, which acts through the leptin receptor,functions as part of a signaling pathway that can inhibit foodintake and/or regulate energy expenditure to maintain constancy ofthe adipose mass. This protein also has several endocrinefunctions, and is involved in the regulation of immune andinflammatory responses, hematopoiesis, angiogenesis and woundhealing. Mutations in this gene and/or its regulatory regions causesevere obesity, and morbid obesity with hypogonadism. This gene hasalso been linked to type 2 diabetes mellitus development. [providedby RefSeq].


Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :Qin, J., et al. J. Hum. Genet. 55(10):704-706(2010)Friedlander, Y., et al. Ann. Hum. Genet. 74(5):387-398(2010)Sarzynski, M.A., et al. Int J Obes (Lond) (2010) In press :Iciek, R., et al. Ginekol. Pol. 81(8):571-577(2010)

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$ 80.00
Cat# BP16666a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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