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SH3BP2 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P78314
Clone Names 100525230
Peptide ID 100525230
Additional Information
Gene ID 6452
Other Names SH3 domain-binding protein 2, 3BP-2, SH3BP2, 3BP2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SH3BP2
Synonyms 3BP2
Function Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. Binds to phosphatidylinositols; linking the hemopoietic tyrosine kinase fes to the cytoplasmic membrane in a phosphorylation dependent mechanism.
Tissue Location Expressed in a variety of tissues including lung, liver, skeletal muscle, kidney and pancreas
Research Areas
Citations (0)

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The protein encoded by this gene has an N-terminalpleckstrin homology (PH) domain, an SH3-binding proline-richregion, and a C-terminal SH2 domain. The protein binds to the SH3domains of several proteins including the ABL1 and SYK proteintyrosine kinases , and functions as a cytoplasmic adaptor proteinto positively regulate transcriptional activity in T, naturalkiller (NK), and basophilic cells. Mutations in this gene result incherubism. Multiple transcript variants encoding different isoformshave been found for this gene.


Lietman, S.A., et al. J. Orthop. Res. 28(11):1425-1430(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Davila, S., et al. Genes Immun. 11(3):232-238(2010)Amaral, F.R., et al. J. Oral Pathol. Med. 39(3):269-274(2010)Shukla, U., et al. J. Biol. Chem. 284(49):33719-33728(2009)

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$ 80.00
Cat# BP16677c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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