PANX3 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q96QZ0 |
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Clone Names | 100422184 |
Gene ID | 116337 |
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Other Names | Pannexin-3, PANX3 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PANX3 (HGNC:20573) |
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Function | Regulator of osteoblast differentiation by functionning as a Ca(2+) channel in the endoplasmic reticulum which regulates calmodulin (CaM) pathways. Allows ATP release into the extracellular space and activation or purinergic receptors. |
Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q8CEG0}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00351} Cell junction, gap junction {ECO:0000250|UniProtKB:Q8CEG0}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q8CEG0}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00351} |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene belongs to the innexinfamily. Innexin family members are known to be the structuralcomponents of gap junctions.
References
Iwamoto, T., et al. J. Biol. Chem. 285(24):18948-18958(2010)Bhalla-Gehi, R., et al. J. Biol. Chem. 285(12):9147-9160(2010)Penuela, S., et al. J. Cell. Sci. 120 (PT 21), 3772-3783 (2007) :Baranova, A., et al. Genomics 83(4):706-716(2004)Bruzzone, R., et al. Proc. Natl. Acad. Sci. U.S.A. 100(23):13644-13649(2003)
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