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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   NACC2 Antibody (C-term) Blocking Peptide   

NACC2 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q96BF6
Clone Names 100617057
Peptide ID 100617057
Additional Information
Gene ID 138151
Other Names Nucleus accumbens-associated protein 2, NAC-2, BTB/POZ domain-containing protein 14A, Repressor with BTB domain and BEN domain, NACC2, BTBD14A, NAC2, RBB
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NACC2
Synonyms BTBD14A, NAC2, RBB
Function Functions as a transcriptional repressor through its association with the NuRD complex. Recruits the NuRD complex to the promoter of MDM2, leading to the repression of MDM2 transcription and subsequent stability of p53/TP53.
Cellular Location Nucleus. Note=Predominantly associated with chromatin
Research Areas
Citations (0)

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BTBD14A (BTB/POZ domain-containing protein 14A), also known as BTBD14, is a 587 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD14A may play a role in transcription regulation.


Rose, J. Phd, et al. Mol. Med. (2010) In press :Humphray, S.J., et al. Nature 429(6990):369-374(2004)

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$ 80.00
Cat# BP16720b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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