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NUP50 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9UKX7
Clone Names 100617118
Peptide ID 100617118
Additional Information
Gene ID 10762
Other Names Nuclear pore complex protein Nup50, 50 kDa nucleoporin, Nuclear pore-associated protein 60 kDa-like, Nucleoporin Nup50, NUP50, NPAP60L
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NUP50
Synonyms NPAP60L
Function Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin- alpha:beta-cargo complex and importin recycling. Interacts with multiple transport receptor proteins including CDKN1B. This interaction is required for correct intracellular transport and degradation of CDKN1B.
Cellular Location Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note=Localizes to the nucleoplasmic fibrils of the nuclear pore complex (By similarity). Dissociates from the NPC structure early during prophase of mitosis. Associates to the newly formed nuclear membrane during telophase.
Tissue Location Ubiquitous. Highest levels in testis, peripheral blood leukocytes and fetal liver
Research Areas
Citations (0)

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The nuclear pore complex is a massive structure thatextends across the nuclear envelope, forming a gateway thatregulates the flow of macromolecules between the nucleus and thecytoplasm. Nucleoporins are the main components of the nuclear porecomplex in eukaryotic cells. The protein encoded by this gene is amember of the FG-repeat containing nucleoporins that functions as asoluble cofactor in importin-alpha:beta-mediated nuclear proteinimport. Pseudogenes of this gene are found on chromosomes 5, 6, and14. Two transcript variants encoding different isoforms have beenfound for this gene.


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Ogawa, Y., et al. Mol. Biol. Cell 21(4):630-638(2010)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)

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$ 80.00
Cat# BP16725c
(40 western blots)
Availability: In Stock
Bulk Size
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